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What is Erectile Dysfunction or impotence?

Erectile dysfunction (ED) is the inability of a man to achieve or maintain an erection sufficient for his or his partners sexual needs. Most men experience this inability at some point in their lives, usually by the age of 40, and are not psychologically affected by it. Some men experience chronic, complete erectile dysfunction (impotence), and others achieve partial or brief erections. Frequent erectile dysfunction can cause emotional and relationship problems, and often leads to diminished self-esteem and depression. It has many varied causes, not all medical, most of which are treatable, and is not an inevitable consequence of ageing.

How it works?
The arteries that feed the spongy tissue in the penis dilate when they receive signals from the brain. The signal is carried by nitric oxide in the blood. It switches on the enzyme which makes a molecule known as cGMP (cyclic Guanosine Monophosphate). This triggers smooth muscle in the artery wall to relax and so the blood vessel dilates . However, the cGMP is broken down by another enzyme known as PDE (Phosphodiesterase) causing the arteries to narrow again - bringing an end to the erection. Kamagra™ inhibits the PDE and stops it from breaking down the cGMP. In this way, the natural erection is maintained. It doesn't last forever - only as long as the natural stimulation remains.

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