Generic Name: diazepam (dye AZ e pam)
Brand names: Valium
What is diazepam?
Diazepam is a benzodiazepine. It affects chemicals in the
brain that may become unbalanced and cause anxiety.
Diazepam is used for the management of anxiety disorders or
for the short-term relief of symptoms of anxiety. Diazepam may also be used to
relieve agitation, shakiness, and hallucinations during alcohol withdrawal and
relieve certain types of muscle spasms. It may also be used to treat seizures,
insomnia, and other conditions as determined by your doctor.
Diazepam may also be used for other purposes not listed in
this medication guide.
Important information know about diazepam
You should not use this medication if you are allergic to
diazepam, or if you have myasthenia gravis, severe liver disease, narrow-angle
glaucoma, a severe breathing problem, or sleep apnea. This medication can cause
birth defects in an unborn baby. Do not use diazepam if you are pregnant.
Before taking diazepam, tell your doctor if you have
glaucoma, asthma or other breathing problems, kidney or liver disease, seizures,
or a history of drug or alcohol addiction, mental illness, depression, or
suicidal thoughts.
Do not drink alcohol while taking diazepam. This medication
can increase the effects of alcohol.
Never take more of this medication than your doctor has
prescribed. An overdose of diazepam can be fatal.
Diazepam may be habit-forming and should be used only by the
person it was prescribed for. This medication should never be shared with
another person, especially someone who has a history of drug abuse or addiction.
Keep the medication in a secure place where others cannot get to it.
Before taking diazepam
Diazepam may be habit-forming and should be used only by the
person it was prescribed for. Diazepam should never be shared with another
person, especially someone who has a history of drug abuse or addiction. Keep
the medication in a secure place where others cannot get to it. You should not
use this medication if you are allergic to diazepam, or if you have:
myasthenia gravis (a muscle weakness disorder);
severe liver disease;
narrow-angle glaucoma;
a severe breathing problem; or
sleep apnea (breathing stops during sleep).
If you have certain conditions, you may need a dose
adjustment or special tests to safely take this medicine. Before taking
diazepam, tell your doctor if you are allergic to any drugs, or if you have:
glaucoma;
asthma, emphysema, bronchitis, chronic obstructive
pulmonary disorder (COPD), or other breathing problems;
kidney or liver disease;
epilepsy or other seizure disorder;
a history of mental illness, depression, or suicidal
thoughts or behavior; or
a history of drug or alcohol addiction.
FDA pregnancy category D. Diazepam can cause birth defects in
an unborn baby. Do not use this medicine while you are pregnant. Tell your
doctor if you become pregnant during treatment. Use an effective form of birth
control while you are using this medication. Diazepam can pass into breast milk
and may harm a nursing baby. Do not use this medication without telling your
doctor if you are breast-feeding a baby.
The sedative effects of diazepam may last longer in older
adults. Accidental falls are common in elderly patients who take benzodiazepines.
Use caution to avoid falling or accidental injury while you are taking diazepam.
Do not give this medication to a child younger than 6 months old.
How should I take diazepam?
Take diazepam exactly as it was prescribed for you. Never
take the medication in larger amounts, or take it for longer than recommended by
your doctor. Follow the directions on your prescription label.
Your doctor may occasionally change your dose to make sure
you get the best results from this medication.
Measure the liquid form of diazepam with a special
dose-measuring spoon or cup, not a regular table spoon. If you do not have a
dose-measuring device, ask your pharmacist for one.
Diazepam should be used for only a short time. Do not take
this medication for longer than 4 months without your doctor's advice. Do not
stop using diazepam suddenly without first talking to your doctor. You may have
increased seizures or withdrawal symptoms when you stop taking diazepam.
Withdrawal symptoms include tremor, sweating, trouble sleeping, muscle cramps,
stomach pain, vomiting, and unusual thoughts or behavior. You may need to use
less and less before you stop the medication completely. Contact your doctor if
this medicine seems to stop working as well in treating your symptoms.
To be sure this medication is not causing harmful effects,
your blood and liver function may need to be tested on a regular basis. Do not
miss any scheduled visits to your doctor.
Store diazepam at room temperature away from moisture, heat,
and light.
Keep track of how many pills have been used from each new
bottle of this medicine. Benzodiazepines are drugs of abuse and you should be
aware if any person in the household is using this medicine improperly or
without a prescription.
What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost
time for your next dose, skip the missed dose and take the medicine at your next
regularly scheduled time. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used
too much of this medicine. An overdose of diazepam can be fatal.
Overdose symptoms may include extreme drowsiness, confusion,
limp or weak muscles, fainting, shallow breathing, or breathing that stops.
What should I avoid while taking diazepam?
Do not drink alcohol while taking diazepam. This medication
can increase the effects of alcohol. Diazepam can cause side effects that may
impair your thinking or reactions. Be careful if you drive or do anything that
requires you to be awake and alert.
Diazepam side effects
Get emergency medical help if you have any of these signs of
an allergic reaction: hives; difficulty breathing; swelling of your face, lips,
tongue, or throat. Call your doctor at once if you have any of these serious
side effects:
confusion, unusual thoughts or behavior;
unusual risk-taking behavior, decreased inhibitions, no
fear of danger;
depressed mood, thoughts of suicide or hurting yourself;
hyperactivity, anxiety, agitation, hostility;
double vision, hallucinations;
weak or shallow breathing;
feeling like you might pass out;
muscle twitching, tremor;
fever, chills, body aches, flu symptoms;
jaundice (yellowing of the skin or eyes); or
urinating less than usual or not at all.
Less serious diazepam side effects may include:
drowsiness, tired feeling;
dizziness, spinning sensation;
blurred vision;
sleep problems (insomnia), nightmares;
muscle weakness, lack of balance or coordination;
slurred speech;
nausea, vomiting, constipation;
headache, memory problems;
drooling or dry mouth;
skin rash; or
loss of interest in sex.
This is not a complete list of side effects and others may
occur. Call your doctor for medical advice about side effects. You may report
side effects to FDA at 1-800-FDA-1088.
What other drugs will affect diazepam?
Before taking diazepam, tell your doctor if you regularly use
other medicines that make you sleepy (such as cold or allergy medicine, other
sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine
for seizures, depression, or anxiety). They can add to sleepiness caused by
diazepam.
Before taking diazepam, tell your doctor if you take any
other seizure medications, or if you are using any of the following drugs:
cimetidine (Tagamet);
ketoconazole (Nizoral);
omeprazole (Prilosec);
phenytoin (Dilantin);
a barbiturate such as amobarbital (Amytal), butabarbital
(Butisol), mephobarbital (Mebaral), secobarbital (Seconal), or phenobarbital
(Luminal, Solfoton);
an MAO inhibitor such as isocarboxazid (Marplan),
phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or
tranylcypromine (Parnate);
medicines to treat psychiatric disorders, such as
aripiprazole (Abilify), chlorpromazine (Thorazine), haloperidol (Haldol),
mesoridazine (Serentil), prochlorperazine (Compazine, Compro), promethazine
(Pentazine, Phenergan, Phenadoz, Promethegan), and others;
narcotic medications such as fentanyl (Duragesic, Actiq),
hydrocodone (Lortab, Vicodin), hydromorphone (Dilaudid), methadone (Dolophine,
Methadose), morphine (Kadian, MS Contin, Oramorph), oxycodone (OxyContin),
and others; or
an antidepressant such as amitriptyline (Elavil, Etrafon),
citalopram (Celexa), doxepin (Sinequan), fluoxetine (Prozac, Sarafem),
imipramine (Janimine, Tofranil), nortriptyline (Pamelor), paroxetine (Paxil),
sertraline (Zoloft), and others.
This list is not complete and there may be other drugs that
can interact with diazepam. Tell your doctor about all the prescription and
over-the-counter medications you use. This includes vitamins, minerals, herbal
products, and drugs prescribed by other doctors. Do not start using a new
medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about
diazepam.
Remember, keep this and all other medicines out of the
reach of children, never share your medicines with others, and use this
medication only for the indication prescribed.
Every effort has been made to ensure that the information
provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and
complete, but no guarantee is made to that effect. Drug information
contained herein may be time sensitive. Multum information has been compiled
for use by healthcare practitioners and consumers in the United States and
therefore Multum does not warrant that uses outside of the United States are
appropriate, unless specifically indicated otherwise. Multum's drug
information does not endorse drugs, diagnose patients or recommend therapy.
Multum's drug information is an informational resource designed to assist
licensed healthcare practitioners in caring for their patients and/or to
serve consumers viewing this service as a supplement to, and not a
substitute for, the expertise, skill, knowledge and judgment of healthcare
practitioners. The absence of a warning for a given drug or drug combination
in no way should be construed to indicate that the drug or drug combination
is safe, effective or appropriate for any given patient. Multum does not
assume any responsibility for any aspect of healthcare administered with the
aid of information Multum provides. The information contained herein is not
intended to cover all possible uses, directions, precautions, warnings, drug
interactions, allergic reactions, or adverse effects. If you have questions
about the drugs you are taking, check with your doctor, nurse or pharmacist.
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